Dose Study Utilizing Ag Containing Markers in 125I Seed for Eye Brachytherapy
DOI:
https://doi.org/10.22399/ijbimes.24Keywords:
125I Seed , Dose Study, Absorbed Dose, FLUKA Environment , Ag Containing MarkerAbstract
Background: Radionuclide therapy (encapsulating beta or gamma radionuclides close to or inside the tumor) for ocular benign growth or malignant melanoma presents as an efficacious treatment modality in the realm of cancer management. This research endeavors to establish a comprehensive protocol for treatment of ocular malignancies, specifically employing iodine-125, (125I) radionuclide. In this study, novel cylinder markers composed of Ag/Ag+Al2O3 were employed to assess the distribution of doses within the tumor region of an eye phantom; Methods: To scrutinize the dose distributions within the tumor, we conducted the study employing the FLUKA Monte Carlo (MC) Environment. In this work, the Ag marker in the 125I new seed has been modeled at the center of the Titanium (Ti) coating; Results: By increasing the depth (distance from the source), absorbed radius dose values decrease. These values in 1 mm drop from 1 cGy/h to 0.079 in a 10 mm radius; and Conclusions: The obtained results validate the effectiveness of the MC method in eye plaque brachytherapy.
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Copyright (c) 2026 Osman Gunay, Roya Roya Boudaghi Malidarreh, Seher Polat, Vladimir Yurivich Ivanov, parisa boodaghi malidarreh, Iskender Akkurt
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