Brachytherapy: Applications and Importance
DOI:
https://doi.org/10.22399/ijbimes.23Keywords:
Brachytherapy, Applicator, Beta emitter, Cancer TreatmentAbstract
Background: This review aims to highlight the importance of brachytherapy in medical physics, specifically, cancer treatment and dosimetry. This type of therapy uses radionuclide irradiation in or in contact with the tumor surface. Based on the target organ, various applicators can be used.Materials and methods: Both clinical and Monte Carlo methods are able to obtain the organ and the neighboring tissues' dose rates.Results: The findings reveal that the Monte Carlo method can only predict the dose range and ranges of dose in organs at risk, and does not give us precise results.Conclusion: In summary, after evaluation of doses in the Monte Carlo method, we should validate them with clinical results.
References
[1] Chargari C, Deutsch E, Blanchard P, Gouy S, Martelli H, Guérin F, Dumas I, Bossi A, Morice P, Viswanathan AN, Haie-Meder C. Brachytherapy: An overview for clinicians. CA Cancer J Clin. 2019 Sep;69(5):386-401. doi: 10.3322/caac.21578. Epub 2019 Jul 30. PMID: 31361333.
[2] Boudaghi Malidarreh R, MH Zakaly H, 2025. Monte Carlo simulation of absorbed dose in water for the INTRABEAM electronic brachytherapy unit using a micro-diamond detector model, 57, 103372.
[3] Mukherjee A, Pandey U, Shaikh SH, Kumar M, Kaushik V, Jagasia P, Kumar SA, Dhami PS, 2022. A facile strategy for preparation of yttrium-90 therapeutic sources for radionuclide therapy. Cancer Biother. Radiopharm. Biother. Radiopharm. 37, 364–371.
[4] Pashazadeh A, Hoeschen C,2022. Comparison of the Y-90 brachytherapy and Ir-192 brachytherapy of skin tumors: a simulation study. Curr. Dir. Biomed. Eng. 8, 388–391.
[5] Y. Bouzekraoui, F. Bentayeb, H. Asmi, F. Bonutti, Energy window and contrast optimization for single-photon emission computed tomography bremsstrahlung imaging with yttrium-90, Indian J. Nucl. Med. 34 (2019) 125–128. https://doi.org/10.4103/ijnm.IJNM_150_18.
[6] X. Chang, L. Huang, J. Liu, Y. Cao, J. Chang, Monte Carlo dosimetry of a novel Yttrium-90 disc source for episcleral brachytherapy, J. Appl. Clin. Med. Phys. 24 (2023) e14140. https://doi.org/10.1002/ACM2.14140.
[7] H. BS, The Collaborative Ocular Melanoma Study (COMS) randomized trial of pre-enucleation radiation of large choroidal melanoma: IV. Ten-year mortality findings and prognostic factors. COMS report number 24, Am. J. Ophthalmol. 138 (2004) 936–951. https://doi.org/10.1016/J.AJO.2004.07.006.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Roya Boudaghi Malidarreh, Iskender Akkurt
This work is licensed under a Creative Commons Attribution 4.0 International License.
